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Neurotensin(8-13) 3TFA(60482-95-3(free base))

CAS No.

Neurotensin(8-13) 3TFA(60482-95-3(free base)) ( —— )

Catalog No. M22782 CAS No.

Neurotensin(8-13)(3TFA) isNeurotensin (NT)fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.The internalization of the receptor induced by neurotensin (8-13) leads to a decrease in the density of the NT1 receptor (NTR1) on the cell surface.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Neurotensin(8-13) 3TFA(60482-95-3(free base))
  • Note
    Research use only, not for human use.
  • Brief Description
    Neurotensin(8-13)(3TFA) isNeurotensin (NT)fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.The internalization of the receptor induced by neurotensin (8-13) leads to a decrease in the density of the NT1 receptor (NTR1) on the cell surface.
  • Description
    Neurotensin(8-13)(3TFA) isNeurotensin (NT)fragment, Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.The internalization of the receptor induced by neurotensin (8-13) leads to a decrease in the density of the NT1 receptor (NTR1) on the cell surface.In ht-29 cells and rat primary cultured neurons, the neurotensin (NT) receptor was down-regulated by high concentrations of extracellular peptides.The representation of cell surface receptors is also different.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    NTR1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    --
  • Formula Weight
    816.99
  • Molecular Formula
    C38H64N12O8
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    OC(=O)C(F)(F)F.CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Elisa García-Garayoa, Peter Bluenstein, Bruehlmeier M , et al. Preclinical evaluation of a new, stabilized neurotensin(8-13) pseudopeptide radiolabeled with 99mTc[J]. Journal of Nuclear Medicine, 2002, 43(3):374-383.
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